Considerations Regarding the Importance of In Vivo Data for the Development of an Alternative to Conventional Skin Irritation Testing

Hajime Kojima
Research Laboratories, Nippon Menard Cosmetic Co., Ltd.

AATEX 11(1):31-38, 2005

Regarding possible alternatives to skin irritation testing using animals, I will comment on the importance of comparing in vivo data with in vitro data from the viewpoint of the specific purposes and needs of product testing. I recommend an alternative method using the results of occluded human patch tests, without of the need for animal testing.

Key words:Kew words: skin irritation, in vivo, alternative, human patch test


(AATEX: Altern. Animal Test. EXperiment.: Alternatives to Animal Testing and EXperimentation)