REVIEW
Considerations Regarding the Importance of In Vivo Data for the Development of an Alternative to Conventional Skin Irritation Testing

Hajime Kojima
Research Laboratories, Nippon Menard Cosmetic Co., Ltd.

AATEX 11(1):31-38, 2005

Abstract
Regarding possible alternatives to skin irritation testing using animals, I will comment on the importance of comparing in vivo data with in vitro data from the viewpoint of the specific purposes and needs of product testing. I recommend an alternative method using the results of occluded human patch tests, without of the need for animal testing.

Key words:Kew words: skin irritation, in vivo, alternative, human patch test


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