Vol.6 Nos.2-3

Original paper

  1. Which Cytotoxicity Tests are Useful for Prediction of Skin Irritation by Surfactants?

    Hajime Kojima, Tomonori Katada and Hiroaki Konishi

    Research Laboratories, Nippon Menard Cosmetic Co., Ltd.,2-7 Torimi-cho, Nishi-ku, Nagoya 451-0071, Japan
     (pp. 79-88)
  2. Effect of Digoxin on Chick Embryos with Hypothyroidism Induced by Thiamazole

    Takashi Sugiyama1, Kazuru Saito2, Hideyo Shimada1,2, Kanji Tsuchimoto1,2 and Yuji Yoshiyama3

    1Division of Pathophysiology, Center for Clinical Pharmacy and Clinical Sciences, School of Pharmaceutical Sciences, Kitasato University,
    2Kitasato Institute Hospital, 9-1, Shirokane 5-chome, Minato-ku, Tokyo 108-8641, Japan
    3Division of Clinical Pharmacy, Kyoritsu College of Pharmacy, 1-5-30, Shibakoen, Minato-ku, Tokyo 105-8512, Japan
     (pp. 89-96)
  3. Genetically Engineered Bacterial Cells Expressing Human Cytochrome P450 as an Alternative Tool in the Prediction of Metabolism and Toxicity of Chemicals in Humans

    Ken-ichi Fujita, Hirotaka Kushida, Hiroshi Iwata, Akihiro Suzuki,Yoshiyuki Yamazaki, Kazuo Nakayama and Tetsuya Kamataki

    Laboratory of Drug Metabolism, Division of Pharmacobio-dynamics, Graduate School of Pharmaceutical Sciences, Hokkaido University, Kita-ku N12 W6, Sapporo, 060-0812, Japan
     (pp. 97-127)
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