Vol.7 Nos. 2-3


Original paper

  1. Development of a Simple Double-layered Cell Culture System Using Caco-2 and TIG-1 Cells as a New Cytotoxicity Test

    Yasuyuki Sakai 1, Tomonori Arai 1,2, Akiyoshi Sakoda1, and Motoyuki Suzuki1,3

    1Institute of Industrial Science, University of Tokyo, 7-22-1 Roppongi, Minato-ku, Tokyo 106-8558, Japan
    2Current address; Mitsubishi Tokyo Pharmaceutical Co. Ltd., 1,000 Kamoshida, Aoba-ku, Yokohama 227-0033, Japan
    3United Nations University, 5-53-70 Jingumae, Shibuya-ku, Tokyo 150-8558, Japan

    (pp. 47 -58)
  2. Color Doppler Echocardiograms Can Measure Hemodynamic Changes of Cardiovascular Systems in Chick Embryos

    Takashi Sugiyama1, Kazuru Saito2, Hideyo Shimada1 and Kanji Tshuchimoto1,2
    1Division of Pathophysiology, Center for Clinical Pharmacy and Clinical Sciences, School of Pharmaceutical Sciences, Kitasato University, 9-1, Shirokane 5-chome, Minato-ku, Tokyo 108-8641, Japan
    2Kitasato Institute Hospital, 9-1, Shirokane 5-chome, Minato-ku, Tokyo 108-8642, Japan

    (pp. 59 - 66)

  3. Selected Presentations from the Symposium entitled Potential and Problems of Alternative Research
    -Alternatives,Biosafety and Ethics in Laboratories with Human Cells-"(November 13-14, 1999, Tokyo)"

    Framework is Indispensable to Promote the Use of Human Material in Pharmacogenetics------69
    Tohru Masui

    Ethical Considerations on the Use of Human Tissues and Cells in Non-clinical Science, Techhnology and Practice-----71
    Toshiharu Matsumura

    Bioethics of Human DNA Sampling-----75
    Hiraku Takebe

    Biosafety in Laboratories Working with Human Materials------77
    Reiko Hirai


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