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6th World Congress on Alternatives & Animal Use in the Life Sciences
-Review progress made toward the 3Rs-



Vol.14, Special Issue
March 31, 2008

Proceedings
Page 1-177
 Page 179-327
 Page 329-507
 Page 509-668
 Page 669-809



Page 509-668

  1. Preliminary study on neutral red uptake assay as an alternative method for eye irritation test
    X. Yang, W. Zhang, Y. Yang, X. Xiong, X. Xie and X. Tan, 509-514.
  2. Establishment and use of 3t3 NRU assay for assessment of phototoxic hazard of cosmetic products
    Y. Yanga, X. Xiong, X. Yang, J. Huan, X. Tan, X. Xie, H. Zheng, Q. Li and X. He, 515-518.
  3. Bhas42 cell transformation assay as a predictor of carcinogenicity
    A. Poth, A. Heppenheimer and S. Bohnenberger, 519-521.
  4. ECVAM key area topical toxicity: Update on activities
    V. Zuang, C. Eskes, C. Griesinger and T. Hartung, 523-528.
  5. Experiences in the development and utilization of an in vitro safety testing program for hair conditioners
    P. Vavilikolanu, C. Lazaro, G. Mun, A. Hilberer, M. Hyder, H. Raabe, R. Curren and G.-E. Costin, 529-534.
  6. Protective effect of melatonin on spinal cord damage after gamma irradiation
    S. Aghazadeh, M. Azarnia, A. Shirazi, S. R. Mahdavi and B. M. Zangii, 535-538.
  7. Does preclinical testing on insects help to predict human myelotoxic potentials?
    J. Berger, 539-541.
  8. Evaluation of health risk due to the exposure to endosulfan in the environment
    M. P. L. Chan, S. Morisawa, A. Nakayama and M. Yoneda, 543-548.
  9. Responsiveness to painful stimuli in anaesthetised newborn and young animals of varying neurological maturity (wallaby joeys, rat pups and lambs)
    T. J. Diesch, D. J. Mellor, C. B. Johnson and R. G. Lentle, 549-552.
  10. Predicting carcinogenicity in humans: The need to supplement animal-based toxicology
    M. E. Long, 553-559.
  11. Systemic testing by the dermal route can be precluded by new non-animal percutaneous absorption strategies
    K. Stoick, K. Nitschke and C. Sandusky, 561-564.
  12. The usage of Daphnia magna as alternative bioobject in ecotoxicology
    V. Tonkopii and I. Iofina, 565-567.
  13. Eco-toxicological effect of polycyclic musks for C. elegans
    T. Mori, A. Inokuchi, M. Nihira, R. Yamamoto, H. Ishibashi, S. Kohra, N. Tominaga and K. Arizono, 569-573.
  14. Three Rs achievements in vaccinology
    C. Hendriksen, 575-579.
  15. Alternatives to the LD50 assay for botulinum toxin potency testing: Strategies and progress towards refinement, reduction and replacement
    D. Sesardic and R. G. Das, 581-585.
  16. 10 years of experience with alternative pyrogen tests (monocyte activation tests)
    I. Spreitzer, B. Löschner, C. K. Schneider, K.-M. Hanschmann and T. Montag, 587-589.
  17. Alternative methods for animal tests in the quality control of biological products in China
    Z. He, 591-593.
  18. The importance of supplier qualification for vendors of materials used in in vitro assays
    A. K. Ulrey, R. D. Curren and H. A. Raabe, 595-600.
  19. Development of defined medium for mouse, monkey and human ES cell culture
    M. K. Furue, J. Na, J. P. Jackson, T. Miyazaki, K. Takada, H. Suemori, R. Hata, N. Nakatsuji, T. Okamoto, J. D. Sato and P. W. Andrews, 601-603.
  20. Chromatin remodelling, a novel strategy to expedite the hepatic differentiation of adult bone marrow stem cells in vitro
    J. De Kock, T. Vanhaecke, V. Rogiers and S. Snykers, 605-611.
  21. Histone deacetylase inhibitors: Opening a new field of research in the development of alternative methods?
    V. Rogiers, M. Vinken, S. Snykers, T. Henkens, J. Fraczek, E. De Rop, J. De Kock, T. Doktorova, A. Lukaszuk, D. Tourwe and T. Vanhaecke, 613-617.
  22. Development of a disposable three-compartment micro-cell culture device for toxicokinetic study in humans and its preliminary evaluation
    H. Nakayama, H. Kimura, K. Komori, T. Fujii and Y. Sakai, 619-622.
  23. ToxCastTM: Developing predictive signatures for chemical toxicity
    R. J. Kavlock, D. J. Dix, K. A. Houck, R. S. Judson, M. T. Martin and A. M. Richard, 623-627.
  24. Impact of systems toxicology on the 3Rs
    J. C. Fuscoe, 629-632.
  25. Percellome toxicogenomics project and its possible contribution to 3R's
    J. Kanno, 633-636.
  26. In vitro assays for evaluating the cellular responses to DNA damage induced by solar UV
    T. Matsunaga, 637-640.
  27. A quantitative in vitro assay to detect biological activity of endotoxin using rabbit peripheral blood
    M. Ochiai, A. Yamamoto, M. Kataoka, H. Toyozumi, Y. Arakawa and Y. Horiuchi, 641-645.
  28. A clinically relevant in vitro pyrogen test using a human cell line that have the similar responsiveness to various pyrogens to that of human peripheral blood cells (hPBC)
    A. Yamamoto, M. Ochiai, K. Kamachi, M. Kataoka, H. Toyoizumi, Y. Arakawa and Y. Horiuchi, 647-653.
  29. Effects of experimental alloys contaning indium for dental use in vitro embryotoxicity test
    K. Imai and M. Nakamura, 655-658.
  30. An advanced in vitro liver tissue model by combination of on-site oxygenation and double-layer coculture with fibroblasts
    M. Nishikawa, N. Kojima, T. Yamamoto, T. Fujii and Y. Sakai, 659-663.
  31. Liver cells culture on three-dimensional micropatterned polydimethylsiloxane surfaces
    F. Evenou, T. Fujii and Y. Sakai, 665-668.



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