AATEX 14(3):937-939, 2009
Fifty years after the publication of The Principles of Humane Experimental Technique by W.M.S. Russell and R.L. Burch there is a heightened interest in the development and application of in vitro methods. The reasons behind this interest in new toxicological methods are numerous. Some are grounded in legislative bans on animal testing, such as the European Union's 7th Amendment to the Cosmetics Directive which prohibits the use of animals to assess the safety of cosmetics and their ingredients. Others are due to the need for a pragmatic approach to large legislated testing programs such as the EU's Registration, Evaluation, Authorization and Restriction of Chemicals (REACH) program. Without the use of in vitro methods it is unlikely that all the proposed toxicity testing could be completed. Other reasons behind the new interest are due to ethical concerns ? either by consumers who wish to purchase products they feel support their moral views about the use of animals, or by toxicologists themselves who feel strongly that non-animal methods should be used whenever possible. .....
(AATEX: Altern. Animal Test. EXperiment.: Alternatives to Animal Testing and EXperimentation)